Acetazolamide in the treatment of acute decompensated heart failure with volume overload New England Journal of Medicine

Acetazolamide in the treatment of acute decompensated heart failure with volume overload New England Journal of Medicine

Abstract background Could acetazolamide, a carbonic anhydrase inhibitor that reduces proximal renal tubular sodium reabsorption, improve the efficiency of loop diuretics, potentially leading to more and faster volume overload in acute decompensated heart failure patients Reduce congestion, it is not known. method In this multicenter, parallel group, double-blind, randomized, placebo-controlled trial, we will treat patients …

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